Type 2 Diabetes – Obese Newborns at Risk for Developing Insulin Resistance


According to a study reported on in July of 2018 in the Journal of Clinical and Endocrinological Metabolism babies born large for their age are at risk for insulin resistance, the cause of Type 2 diabetes. Scientists at the Shanghai Jiao-Tong University in Shanghai, China, and some different research facilities in Canada found what may be the reason for the high risk of Type 2 diabetes seen in adults born large for their ages.

The researchers included…

  • 106 large-for-gestational-age, (overweight or obese at birth) and
  • 106 appropriate-for-gestational-age (normal weight at birth) infants.

Larger infants had higher levels of blood insulin and leptin, a hormone that lets the brain know when the body has eaten enough food. Larger babies had higher amounts of insulin for their blood sugar levels, indicating their body was resistant to the insulin. They also showed more proinsulin, a molecule that divides to make insulin, indicating insulin was not being produced at a fast enough pace. What this reveals is their beta cells, the pancreatic cells responsible for producing insulin were not working efficiently

While low insulin sensitivity causes Type 2 diabetes, poor beta cell function is responsible for the Type 1 variety of diabetes. It has been suggested the two could be stages of the same disease. In any case, mothers need to take care of their babies weight gain to help prevent obesity developing and to give their baby a healthy start.

The fetus stores fat when they are exposed to high levels of blood sugar, just as adults do. During pregnancy, a condition called Gestational diabetes can develop at around 24 to 28 weeks. At this time the mother’s blood sugar levels rise and sends high levels of sugar to the fetus. To prevent developing Gestational diabetes women need to maintain a healthy body weight before conception and gain only the amount of pregnancy weight advised by their doctor or midwife. If Gestational diabetes is diagnosed diet, insulin, or oral medication may be prescribed to keep blood sugar under control.

All pregnant women need to eat a healthy diet high in nutrients…

  • a lot of colorful fruits and vegetables supply vitamins and minerals without adding empty calories.
  • the fiber in plant-based foods helps to control blood sugar levels by slowing the absorption of sugar.
  • activities such as walking or swimming also help keep blood sugar levels from rising too high

and could help promote health for generations to come.



Source by Beverleigh H Piepers

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