Signaling switch in pancreatic beta-cells determines anti-diabetic drug effectiveness

An international research group has clarified the action mechanism of incretin-based drugs in the treatment of diabetes. The research group headed by Professor Seino Susumu included Researcher Okechi Oduori et al. (Division of Molecular and Metabolic Medicine, Kobe University Graduate School of Medicine), Professor Shimomura Kenju (Fukushima Medical University), Professor Patrik Rorsman (University of Oxford, UK/University of Gothenburg, Sweden), and their teams.

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