Several significant cholangiocarcinoma risk factors identified



Results from a systematic review and meta-analysis revealed 13 risk factors for intrahepatic and extrahepatic cholangiocarcinoma, the most significant of which included biliary cysts and stones, cirrhosis, hepatitis B and hepatitis C.
Additionally, although diabetes was not among the strongest risk factors, increasing global rates of diabetes may be contributing to rising rates of cholangiocarcinoma (CCA).
“CCA typically presents late with non-specific symptoms,” Oliver Clements, MD, from Imperial College London in the United Kingdom, and colleagues wrote. “This is compounded



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