Researchers discover sex-specific differences in neural mechanisms for glucose regulation



Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive. The authors of the study, published online in the Proceedings of the National Academies of Sciences (PNAS), hypothesize that the metabolic ‘switch’ mediated by estrogen may provide clues to the increased risk of insulin resistance and diabetes among post-menopausal women.



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