Researchers discover previously unidentified mechanisms of obesity-induced insulin resistance

A research team at the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has discovered the potentials of a SECISBP2 protein in adipose tissue macrophages (ATMs) as a therapeutic biomarker in the treatment of chronic diseases such as type 2 diabetes, hyperlipidemia, cardiovascular diseases and cancers caused by obesity-induced insulin resistance. The findings, signaling a breakthrough for a new direction towards treating these diseases, were published in Science Advances, a top-tier and internationally recogniZed academic journal. The research team was led by Dr. Feng Yibin, Associate Director of the School of Chinese Medicine, HKUMed.

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