Patients showing more DNA methylation at some genome sites found to be more likely to fail to respond to metformin

A team of researchers affiliated with multiple institutions in Europe has found a connection between patients who show more DNA methylation at some genome sites and a higher likelihood of failing to respond to metformin. In their paper published in the journal Science Translational Medicine, the group describes their genomic study of hundreds of type 2 diabetes patients and what they learned from them.

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