Long-term culture of human pancreatic slices reveals the regeneration of insulin-producing cells in real time



Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of pancreatic slices to study the regeneration of the human pancreas in real time. The results, published today in the journal of Nature Communications, demonstrate for the first time that extended cultures of near-intact human pancreatic tissue retain the ability of the live organ to replenish insulin-producing beta cells. The use of this system as a model to study pancreatic regeneration could have important therapeutic implications for the treatment of diabetes.



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